Antipyrinum

Antipyrinum.

Phenazon (Phenyl-dimethyl-pyrazolon). C11 H12 N2O. A product of coal tar through toluin. Solution and trituration.

Dysmenia. Enuresis. Epilepsy. Epistaxis. Erythema. German measles. Headache. Heart, paralysis of. Mind, deranged. Respiration, Cheyne-Stokes. Scarlatina. Throat, sore. Toothache. Urticaria.

Antipyrine is known from the poisonous effects it has produced in old-school practice. Many fatal cases have been recorded, and there can be little doubt that its injudicious use has determined a fatal issue in many cases that have remained unrecorded. Its action is very like that of Antifebrin in producing collapse, but it has more effect on the skin, causing scarlet rash and oedema. A young lady patient of mine who took Antipyrin on her own account, whenever she thought she might be going to have a headache, developed intense dysmenorrhoea (to which she was not subject), with depression.

This was only removed after she had discontinued the drug. Later on she took Phenacetin, with the result that an eruption of erythema appeared on both cheeks, which peeled after a few days, and recurred persistently. It would seem from the above that the drug is homoeopathic to some forms, at least, of neuralgia. One patient had Cheyne-Stokes respiration.

Erythema appears first on face and arms, last on legs. Hansen mentions its use in enuresis and epistaxis. > Hot drinks.

Compare: Anilinum (skin). Antefeb.; Ars.; Chloral; Acon. (numbness; rapidity of attack). Antidoted by: Bell. The symptoms are much intensified in persons addicted to coffee in excess.

Headache, with toothache; pain behind both ears of tearing character.—Snapping sensation in head.

Buzzing in ears.

Tingling burning in nose, with sneezing and running from eyes and nose; nose and face swollen.—Coppery smell which comes and goes.

Oedema; dusky red face.

General toothache, together with headache; pain behind both ears of a tearing character.

Tingling burning in gums, mouth, and throat.—Lump in mouth about an inch thick just below level of upper teeth (passed away in half-hour).

Dryness, burning, swelling, l. side of throat with aphonia; l. tonsil white and swollen.—Tight, constricted feeling.

Incontinence of urine.—Amount diminished.

Cheyne-Stokes breathing.—Hoarseness following aphonia.

Pulse feeble and rapid.—Fainting spells.

Feeling of numberless pins pricking him down each side of neck.

Pains in limbs.—Limbs swollen.

Cramp in r. arm.—Fingers of r. hand clenched in the form of a claw.

Feeling of numberless pins pricking him down each side of the neck, extending down r. chest and abdomen, particularly severe r. side of scrotum and r. testicle, also in legs and feet, severely r., slightly l Sensation as if contents of chest and abdomen drawn upwards, felt he was "drawn in a ruck," and, being unable to stand, fell on the floor Trembled violently all over, had cramp in r. arm Epileptic attacks, with partial unilateral twitching; contraction of muscles; chattering of teeth; jactitation

Cyanosis Collapse Throbbing all over body Sensation as if inside of body were filled with ice.