Tabacum
Clarke - Dictionary of Practical Materia Medica · John Henry Clarke · 26,808 χαρακτήρες · πηγή ↗
General EN
Tabacum.
Nicotiana tabacum. Tobacco. N. O. Solanaceae. Tincture of the fresh leaves collected before the flowers are developed.
Clinical EN
Amaurosis. Anaemia. Angina pectoris. Anus, prolapse of.
Apoplexy. Asthma. Backache. Brain, anaemia of.
Brain-fag. Catalepsy. Cholera. Cholera infantum.
Colour-blindness. Constipation. Diarrhoea. Epilepsy.
Freckles. Glands, enlarged. Heart, intermittent. Hernia.
Hiccough. Idiocy. Leg, jerking of. Lip, cancer of.
Masturbation, effects of. Ménière's disease. Oesophagus, stricture of. Optic neuritis.
Pregnancy, pruritus of; sickness of; toothache of. Prostatorrhoea. Pruritus. Pyrosis.
Rectum, paralysis of; stricture of. Sea-sickness. Speech, embarrassed. Strabismus.
Tetanus. Toothache. Varicocele.
Characteristics EN
Nicotiana tabacum received its specific name from Jean Nicot, French ambassador to Portugal, who was the means of introducing the tobacco plant into France about 1560. When Columbus and his followers landed in Cuba in 1492 the practice of smoking tobacco was in common use among the natives throughout the island, and also throughout the continent of America. On their return to Spain the practice rapidly spread throughout the Peninsula. Sir Walter Raleigh and his companions introduced the practice into England in 1586.
From that time the cultivation, manufacture, and use of tobacco, either by smoking, snuffing, or chewing, rapidly became universal. The symptoms of the pathogenesis are composed partly of provings made by Lembke, Schreter, and others, and partly of poisonings and over-dosings. Several instructive articles on tobacco appeared in the Homoeopathic News of 1897, from the pen of M. E.
Douglass, then practising at Danville, Virginia, in the midst of tobacco plantations. His third article (July, 1897) was devoted to the "medicinal uses" of Tobacco; and it seems that it is regarded as a perfect panacea by the Virginians for diseases of men and cattle. One use he mentions is as a palliative for bee-stings and mosquito-bites. A portion of a leaf is moistened with vinegar and applied to the part.
This is interesting, as Ipec., one of the antidotes of Tab., has a similar reputation. Strong tobacco-juice is the most effectual destroyer of the burrowing-flea, Chigoe. For headache leaves of Tobacco are moistened with vinegar or camphor solution, and applied to the forehead and nape. The pain is allayed and sleep induced.
The local application over the pit of the stomach relieves nausea. Douglass made in involuntary proving on himself when about twenty. He was attending an evening writing-class, when a class-mate gave him a bit of tobacco to chew, and he put it in his mouth. In a few minutes the bell rang and he took his seat, after first removing the tobacco.
He soon began to feel dizzy, and could not distinguish his copy; the letters danced all over the page; a cold perspiration broke out on the forehead, and extended all over the body. He felt a deathly nausea at his stomach; his hands trembled so that he could not hold pen to paper. He felt so weak and faint he feared he would fall out of his seat. His desk-mate helped him out of the house into the cold air, and gave him a sour apple, bidding him eat it.
It did not seem possible, but he finally tried, and was so much relieved that he ate it all. In half an hour he was able to return to the class, but was so weak and tremulous, he did not attempt to write. The nausea was the first symptom to disappear, then the cold perspiration. The dizziness, trembling, and excessive weakness did not entirely leave till next day.
Since then Douglass has used small doses of vinegar in acute symptoms of nicotine poisoning, either chewing or smoking, with excellent results. Nothing, he says, relieves the sensation of constriction of the oesophagus (in his own case the symptom was a very disagreeable one, "as of a hand clutching the throat") so quickly as vinegar. One of Douglass's patients, a young man in good health, who was very fond of cigars, was certain, if he smoked two in an evening, to have an emission on the same night, sometimes with, but oftener without, dreams.
Next day he was prostrated, hypochondriacal, tongue furred with a thick, fuzzy, yellow coat at base; and dull, occipital headache. Prostatorrhoea and impotence are also among the effects of Tab. The constrictive sensation is not confined to the throat; it affects the rectum, bladder, and chest. There is violent rectal tenesmus; and there is also paralysis and prolapsus ani.
The vesical sphincter is paralysed, there is debility of urine, and enuresis. Two of Lembke's provers, students accustomed to smoke and drink coffee and beer, had incontinence of urine; in one the quantity of urine was not increased, but it was "passed more frequently, and dribbled away involuntarily, with slight itching of urethra in the case of the other the urine was increased, pale, and he "had to pass it several times in the night, almost amounting to incontinence." The power of Tab. to paralyse sphincters and also morbid constrictions accounts for its traditional use in cases of strangulated hernia and obstruction of the bowels, which has been confirmed in homoeopathic practice.
Renal colic comes under the same heading. The same pair of opposites—relaxation and constriction—are seen in the weakness and paralysis on the one hand, and the convulsions on the other. All shades of nervous tremors, faintings, cramps, jerkings, and restlessness are noted, and it is by its power of antidoting these conditions that Tab. holds its place in society. "After an unusually vexatious day," says Douglass, "when I am in that unpleasant condition of mind when it seems as though the slightest word would cause an outburst of passion, nothing else does me quite so much good as a smoke." This is a central nervous action, and if too much indulged leads to degeneration of nerve tissue, as seen in tobacco-blindness.
Tab. also produces a condition like brain-fag; inability to concentrate thoughts; this may even go on to a state of idiocy. Silly talking in boys. A curious state was induced in Mr. Harrison (C.
D. P.), who slept in the cabin of a sloop, the cabin being full of large packages of tobacco. His sleep was harassed by wild and frightful dreams, and he suddenly awakened about midnight, bathed in a cold dew, and totally unable to speak or move. He knew perfectly where he was, and recollected what had occurred the day before; but could not make any bodily effort whatever, and tried in vain to get up or change his position.
"Four bells" was struck on deck, and he heard the sounds (though rather, it seemed, through their vibrating in his body than by the ears); and he was conscious of other things that occurred—so he was not dreaming. At length be became totally insensible for a time, till a roll of the ship roused him, and he awakened and got on deck. His memory was totally lost for a quarter of an hour; he knew he was in a ship, but nothing more. While in this state he saw a man drawing water, and asked him to pour a bucket on his head.
This was done, and all his faculties were instantly restored; and he acquired a most vivid recollection of a vast variety of ideas and events which seemed to have passed through his mind, and that had occupied him during the time of his Supposed insensibility The nutrition is profoundly influenced by Tab., and it probably retards growth in children. It produces a deathly sinking and craving at the stomach, and it is no doubt by virtue of this, acting homoeopathically, that Tab. enables persons who cannot have proper meals to endure starvation better than they otherwise would.
Decaisne (C. D. P.) observed the effects of smoking on youths, aged from 9 to 15. Among the effects were: Bruit in carotids and diminution of red corpuscles of the blood.
Palpitation. Deficient digestive power. Sluggish intellect. Craving for alcoholic stimulants.
Epistaxis. Ulcerated mouth. "The younger the boy, the more marked the symptoms; the better fed suffer least." "Rapid emaciation, especially of back and cheeks" has been noted among the effects. Tab. has a number of backaches, and some are peculiar.
C. M. Boger (Hahn. A., xxxviii, 41) cured this with Tab. cm: Backache persistent;
< lying down, > walking; history of anginoid attacks. in cases of cholera, sea-sickness, sickness of pregnancy, renal colic, strangulated hernia, &c., the keynote symptoms are: deathly nausea, pallor, coldness; icy cold surface, covered with cold sweat; vomiting violent, as soon as he began to move, > on deck and in fresh air. Terrible faint, sinking feeling at pit of stomach. Terry cured a case of sea-sickness with heat along spine from nape down; cold sweat; then vomit. He also cured a case of Ménière's disease with a feeling as if sea-sick.
A keynote symptom of much importance in many abdominal cases is: > by uncovering abdomen. Child wants abdomen uncovered; it > nausea and vomiting. There may be coldness of the abdomen at the same time. Tab. produces a number of skin affections, notably pruritus.
Teste cured with it several cases of freckles; he repeated the remedy and gave it for weeks at a time: "A country girl had her face and hands covered with freckles, two-thirds of which disappeared completely [under Tab.] in summer, the season in which they are most frequent and obstinate." Burnett told me that an infusion of tobacco is a popular German remedy for scrofulous glands. Cooper gives as in indication, "intermittent heart in old people." E. T. Blake (H.
R., ii. 68) records a case of rheumatism with rigid joints and spinal insomnia in a lady, 40, who had been heavily drugged with narcotics before he saw her. "Whenever she composed herself for sleep, just as she was lapsing into unconsciousness, the knees would attempt to fly up towards the chest with an abrupt jerk, tearing painfully at the acetabular adhesions." Other symptoms were: sweating, impaired memory, hypochondriasis, drumming in the ears, facial as well as crural clonus, white tongue, epigastric sinking, alternating with nausea and flatulence, heart action increased by day, diminished down to severe fainting during the night.
Tab. 12 gave three hours' refreshing sleep the first night, more the second, and after the third the leg-jerk departed for good. C. W. (H.
W., xxvi. 207) was troubled with spasm of lower jaw, < out of doors. No remedy did good till he remained one evening with two friends who were smoking, and got himself well saturated with the smoke. That cured him. Slight subsequent returns were always removed by Tab.
J. W. Scott (H. P., xvi. 420) observed a case of epileptiform convulsions brought on by tobacco.
For five months the patient had two attacks weekly, and they grew worse in spite of treatment till the tobacco was discontinued. Sensations are: Sensation of excessive wretchedness. As if struck by a hammer on right side of head. As if a band round head.
As if brains were being bored out. As if black dots filled visual field. As if ears were closed. As of a plug in oesophagus.
As if throat gripped by a hand. As if sea-sick. As if stomach were relaxed. As if chest too tight.
As if a crowbar were twisted round heart. The symptoms are: > Uncovering abdomen. < By pressure. < Motion of vessel.
< Lying; > walking. Lying on left side = palpitation. Motion (even least) <.
Coughing = hiccough; stitches in pit of stomach. Rising <. < Morning: vomiting; diarrhoea; sickness of pregnancy; cramps in fingers. Thirst < night.
Sight < evening. > In open air; (ear symptoms <). > Cold affusion to head.
< Indoors. Symptoms come in paroxysms; are periodical. < By stimulants. Weeping >.
Vomiting >. Music pains in ears.
Relations EN
Antidoted by: Vinegar, Sour Apples, Camph., Coff.; Ipec. (primary effects: vomiting); Ars.
(effects of chewing tobacco); Nux (bad taste in mouth in morning, amblyopia); Phos. (palpitation, tobacco heart, amblyopia, sexual weakness);
Spig. (heart affections); Ign., Puls. (hiccough);
Clem. (toothache); Sep. (neuralgia in face and dyspepsia, chronic nervousness);
Lyc. (impotence); Wine (spasms, cold sweat from excessive smoking). Plant. maj. has sometimes caused aversion to tobacco.
Gels. (occipital headache and vertigo); Tab. 200, or 1,000 for the craving when discontinuing its use. Antidote to: Cic., Stram.
Compare: Nicotinum. Cold sweat, Ver. (Ver. on forehead; Tab. all over).
Coldness in abdomen, Colch., Elps., Lach. Spasmodic pains along l. ureter, Berb. Ménière's disease, Salicin. Incarcerated hernia, Aco., Nux, Op., Sul.
Chills or creeps precede headache (Chel., accompany headache). Sinking immediately after meals, Ars., Cin., Lyc., Sel., Stp., Ur. nit. Hair sensation, K. bi., Sil. (Tab., in eye).
Blindness, optic atrophy, Carb. s., Benz. din., Filix. m. Emissions, heart, anaemia, Dig. Retracted abdomen, Pb. Jerking of legs in bed, Meny.
As if a hand clutching throat (Bell., intestines).
Mind EN
Gloomy melancholy
Inclination to weep
Anguish and inquietude, generally in the afternoon, > by weeping
Restlessness, which prompts continual change of place
Dislike to labour and conversation
Excessive vertigo; mental faculties much impaired; cannot read or study; sufferings from abuse of tobacco
Difficulty of concentrating mind for any length of time on one subject
Feels as if some one were coming to arrest him, or murder him; always with singing in ears (produced—R.
T.
C.)
Suicidal tendency, gloomy forebodings, inclined to hang down head, breath becomes short, appetite goes (produced—R.
T.
C.)
Feels intoxicated, hands and feet tremble
Over-excitement and great liveliness, with songs, dancing, and great loquacity
The Mexican priests incite courage and bravery by means of an ointment of tobacco
Abject cowardice, thinks he is going to die and is in extreme terror of death (from smoking many cigars
J.
H.
C.)
Frequent laughter without cause
Silly talk, cannot stop; loss of memory.—(Attacks of silliness; cannot help talking sillily and memory goes, blames himself for things, inclines to suicide and despair
R.
T.
C.)
Idiotic; epileptic idiocy
Concourse of confused ideas
Cataleptic state
Stupor
Coma.
Head EN
Emptiness and confusion in the head
Dizziness
Vertigo, which often produces loss of consciousness, with nausea (< indoors;
> in open air), and pains in head and eyes
Vertigo < on rising and looking up—brought on by immoderate use of cigars
Giddiness in occiput
Headache, with nausea and vertigo
Excessive heaviness of head
Pressive headache, esp. above eyes, vertex, and temples
Shootings in head
Headache from one temple to the other, involving orbits, or with shooting in l. eye, > from cold
While passing urine, suddenly attacked with pains in head, so severe he screamed for assistance; immediately followed by vomiting
Congestion of blood in head, with internal heat, and throbbing in temples
Neuralgic headache, sensation as of sudden blows struck by a hammer
Periodical sick-headache from fatigue or excitement
Tightness in head as though a band stretched round it, disturbance of vision, tinnitus, and vertigo
Headache > in the open air
Burning and tingling sensation in exterior of head
Trembling of head
Hair falls out
Formication above l. temple.
Eyes EN
Pain in eyes, as from much weeping
Aching in eyes, extending into bottom of orbits
Sensation, as if there were a hair in eye.
Smarting in eyes
Heat and burning sensation in eyes, with redness
Contraction of the lids
Pupils: dilated and insensible; irregularly dilated; contracted
Amblyopia with intolerance of light
Loss of sight on looking steadily at anything white
Confused sight, in evening, as if looking through a veil
Sees as through a fog, and hears as through cotton wool (produced—R.
T.
C.)
Squinting when trying to read
Insufficiency of internal recti
Sparks and black specks before eyes
Central colour scotoma
White or grey atrophia of optic nerve
Optic neuritis
Sudden failure of vision
Tobacco-blindness commences in one eye, generally r.; sight < evening
Photophobia.
Ears EN
Shootings in ears, esp. in open air, and when listening to music
Hyperaesthesia to music and loud talking
Jerking tearing in r. ear, and in front of it externally
Burning heat and redness of the ears
Hard reddish swelling behind (l.) ear, with shootings
Ringing; roaring; rushing; humming in ears, < by loud noise or going into open air
Tinnitus and vertigo
Fluttering in r. ear both heard and felt.
Nose EN
Burning sensation and tingling in the nose
Diminished power of smell, which, however, is very sensitive to odour of wine; fumes all but intoxicate her
Frequent sneezing
Dryness and obstruction of nose.
Face EN
Deadly paleness of face (during the nausea; face collapsed, cold sweat on)
Burning heat in face, with redness, sometimes of one cheek only, and paleness of the other
Face covered with cold sweat
R. cheek glowing, the other pale
Red spots on face
Tearings in bones of face (and teeth, in evening)
Pimples on cheeks, wings of nose, and corners of mouth
Violent tearing in r. facial bones and teeth
Granulated tuberosities on cheeks
Emaciation of face
Lips dry, burning, rough, and cracked
Epithelioma of lip (27 per cent. in men; 1 1/2 in women)
Eruption on commissures of lips
Lancinating pains in maxillary joint, when laughing.
Teeth EN
Toothache, with drawing and tearing pains
Lancinations in carious teeth, when masticating
Violent tearing in r. teeth
Throbbing or jumping pains in teeth
Drawing pain in gums
Gums pale and parched.
Mouth EN
Dryness of the mouth and tongue, with violent thirst
Tongue feels swollen
Tongue: trembles; white; red; furred; dry and parched; covered with blackish-brown crust
Frothing from the mouth
Profuse salivation
Accumulation of white, tenacious mucus in mouth and throat, which must be frequently expectorated
Swelling of glands under tongue
Weak, interrupted speech
Drawling, monotonous style of reading.
Throat EN
Roughness, dryness, and scraping in throat, as from a foreign body
Dry, hot, sulphur feeling in throat, with dry, parched mouth comes on after dose of Ø and remains for a week off and on, but generally < in morning after sleep (R.
T.
C.)
Throat dry, can hardly swallow
Crawling and tickling in throat
Swallowing very painful from spasms in throat
Peculiar sensation of plug in oesophagus, with constant dull pressure
Redness of fauces
Burning in pharynx
Accumulation of viscid mucus in throat.
Appetite EN
Mawkish and clammy, or bitter and sour taste
Acid taste of all food
Acidulated taste of water, as if it contained wine
Adipsia, and dread of water
Great thirst;
< at night
Absence of hunger and appetite
Constant hunger, with nausea if nothing is eaten.
Stomach EN
Frequent empty and noisy risings
Sour, burning risings
Pyrosis
Spasmodic hiccough
Frequent nausea, esp. during movement, often inducing syncope, with deadly paleness of face, disappearing generally in open air
Deathly nausea, with vertigo, in paroxysms, body covered with cold sweat; sea-sickness
Nausea, with inclination to vomit, sensation of coldness in stomach, or pinchings in abdomen
Vomiting of water only, with yellow and greenish reflection before eyes
Vomiting of acid serum, often mixed with mucus
Violent vomiting; easy, of sour liquid; watery, insipid, sometimes bitter in morning
The vomiting is renewed by the slightest movement
Stomach-ache
Squeezing, contractive cramps in stomach, sometimes after a meal, often accompanied by nausea, and an accumulation of saliva in mouth
Shootings in the scrobiculus, which pass through back
Relaxation, and sensation of coldness or burning in stomach
Sinking at the pit of stomach
Dreadful faint feeling in stomach.
Abdomen EN
Hepatic pain, when pressing on the part
Hepatic and renal regions sensitive to pressure
Pressure in hepatic region, as from a heavy body
Shooting in hepatic region
Shootings in the l. hypochondrium
Great sensitiveness of abdomen to slightest touch
Uncovering abdomen > nausea and vomiting
Painful distension of abdomen
Pressive pains in abdomen, esp. in umbilical region, with spasmodic retraction of that part
Violent burning in abdomen, horrible pains, must shriek
Nocturnal tearings in abdomen
Pinchings and borborygmi in abdomen
Incarcerated hernia.
Stool And Anus EN
Constipation
Chronic constipation, great pain and tympanitic distension of intestines; great dyspnoea
Stools clay-colour or mottled grey and brown
Habitual constipation; paralysis of rectum; spasm of anal sphincter
Prolapsus ani; great drowsiness during day when trying to study
Frequent tenesmus
Soft faeces of consistence of pap, also at night
Violent pain in small of back during soft stool
Shifting of flatulence, formed by sudden, papescent, yellow-green or greenish, slimy stools with tenesmus
Violent diarrhoea, fetid or yellowish green slime; also at night, accompanied and followed by violent tenesmus, and burning sensation in anus
Cholera-like stools; watery, urgent, painless.
Urinary Organs EN
Renal colic; violent pains along ureters; cold sweat; deathly nausea
Paralysis of sphincter, constant dribbling
Enuresis
Urine yellowish-red, with increased secretion
Inflammation of the orifice of the urethra.
Male Sexual Organs EN
Frequent erections
Flow of prostatic fluid
Nocturnal emissions; until waking
Genital organs flabby; no erections or sexual desire
Varicocele.—(Masturbation and its consequences
R.
T.
C.)
Female Sexual Organs EN
Retarded and profuse catamenia
Leucorrhoea, like sanguineous water
Leucorrhoea of serous liquid after the menses
In climacteric period, also during menses; subjective coldness; epigastric sinking, palpitation, severe diarrhoea, muscular relaxation, excessive sense of wretchedness
Morning sickness of pregnancy; nausea and vomiting, patient dreads least movement
During pregnancy, insupportable pruritus over whole body, pyrosis, toothache, and other gastric symptoms.
Respiratory Organs EN
Dry cough, excited by a tickling in throat, in morning and towards evening
Cough = in pit of stomach sensation as of a wound by some sharp instrument
Cough, with hiccough (at same time), almost suffocating;
(or hiccough after every paroxysm of whooping-cough)
Difficult respiration
Paroxysm of suffocation.
Chest EN
Oppression of the chest, with anguish
Constriction of the chest
Pressure on the chest and sternum
Shootings in chest and sides of chest, sometimes when drawing breath
Sticking under sternum with inability to take a deep breath.—(A trembling, frightened feeling across pit of chest with sudden and irregular sinkings
Nervous indigestion, constant sinking in chest
R.
T.
C.)
On taking a deep breath it seemed as if chest were too tight
Sensation as if a crowbar were pressed tightly from r. breast to l. till it came and twisted in a knot around heart, which stopped, then leaped violently; after the attack heart missed every fourth beat
Pain, as from excoriation, in chest, during a meal
Itching pimples on chest.
Heart And Pulse EN
Sudden attacks of extreme faintness; feeling of oppression around cardiac region
Angina pectoris (single doses of Ø relieved much; not to be repeated often
R.
T.
C.)
Feeble, irregular pulse
Palpitation of heart, when lying on l. side.
Neck And Back EN
Stiffness of the neck
Head drawn back in convulsions
Neuralgic pains in neck and between shoulders
Burning under scapula
Neuralgia of back with tightness of throat
Contractive pains in the loins, esp. after a stool
Violent pain in small of back and loins (renal calculi)
Throbbing in sacral region, evening
Pain in small of back and loins, esp. after sitting
Intolerable pain in small of back much < while sitting
Pains in small of back, constriction; esp. after a stool
Pressive pain in lumbar region on rising from a seat and beginning to walk, goes off on walking
Emaciation of the back
Red, itching eruption on the back.
Upper Limbs EN
Painful weakness of hands and arms, which are, as it were, paralysed
Constant need to stretch arms
Shootings and drawing in shoulders
Red spots on shoulder, which burn when they are touched
Tension in arm, esp. in elbow
Pain and shootings in l. arm, which disable it and prevent its extension.—(Coldness and trembling of the limbs), trembling of hands
Cold perspiration on hands
Cramps in the arms and hands
Cramps in single fingers, esp. while washing; early morning
Cramps and tingling in fingers
Swelling of fingers
Itching pimples on fingers.
Lower Limbs EN
Burning pain in knee and soles
Legs icy cold from knees down
Shooting in knee and ham
Flexion of knees, when walking
Cramp in toes, extending into knees
Jerking of legs in bed
Tingling, crawling, from knee to toes
Tension in leg when walking, from knee to foot
Trembling and paralytic weakness of feet.
Generalities EN
Pressive pains, with agitation throughout body, and anxious perspiration Sudden breaking out of cold, clammy sweat; with much nausea, feeble, irregular pulse; collapse Cramps and tingling in limbs Restlessness, wants to change place continually
Gait slow and shuffling, difficulty in ascending stairs Excessive emaciation Anaemia of boys and girls, particularly with brain symptoms (cured with dilutions R.
T. C.) Paralytic and painful weakness of limbs Trembling of limbs
Great general lassitude Jerkings throughout body, with pulsation and palpitation of the heart Convulsions, head firmly drawn back, with rigidity of muscles at back of neck; constantly recurring rigid tetanic spasms, muscles of back being principally affected, till death a week after he chewed the tobacco Epileptiform convulsions
Symptoms < on l. side; from great heat or great cold, and esp. in stormy weather; from walking, riding in a carriage, and jar of a railway train.—> In the open air; from vomiting.
Skin EN
Itching in skin, as from flea-bites
Itching over the whole body
Eruption of itching pimples, or vesicles, with yellow serum and red areola.
Sleep EN
Urgent inclination to sleep, esp. after a meal, and towards evening, with frequent yawnings
Retarded sleep in evening, and difficulty in waking in morning
Stupefying sleep at night
Disturbed sleep at night, with fright
Nightmare.
Fever EN
Pulse full, hard, and rapid, or small, imperceptible, intermittent, slow
Coldness and shivering, sometimes with chattering of teeth
Coldness of legs from knees to toes; warm body, cold hands
Chilliness after eating and drinking
Frequent attacks of shuddering, sometimes with flushes of heat
Permanent shuddering, from morning till evening
Perspiration at night
Viscid cold sweat, with intermitting pulse
Cold sweat, in hands, on forehead and face.