Atropinum
Clarke - Dictionary of Practical Materia Medica · John Henry Clarke · 3,748 chars · source ↗
General
Atropinum.
Atropine. An alkaloid of Belladonna. C17 H23 NO3. The effects of the Sulphate of Atropine, the preparation most in use, are included. Solution.
Clinical
Blepharospasm. Convulsions. Enuresis. Epilepsy. Eyes, affections of. Gastric ulcer. Locomotor ataxy. Mania. Neuralgias. Pancreatitis. Spinal irritation. Stammering. Tetanus. Vision, disorders of. Wryneck.
Characteristics
Atropine, as the most active principle in Belladonna, produces, as we should expect, most of the characteristic effects of that drug; but at the same time the two are not identical. Atrop. produces hyperaesthesia of the sensory nerves. The most numerous symptoms have been observed in the eyes. All kinds of illusions of vision.
Everything appears large. Motes over everything. I once cured with it a lady who had an appearance of shadows passing over whatever she looked at. It has shown an affinity for the pancreas, which relates it to Iod., Kali iod., and Iris.
A case of chronic wryneck, of three years' standing, was relieved and finally cured within two weeks by injections of 1/120 into the platysma, the dose being increased up to 1/20th. This was in old-school practice. It has caused difficulty of speech: frequent stuttering, especially at words difficult to pronounce; articulation indistinct, rapid and chattering.
Relations
It antidotes: Muscarine and Opium. It is antidoted by: Op. and Physostigma. Like Bell., it is a right-side medicine.
Mind
Frenzied with excitement
Spectral illusions; sees insects and crawling things and tries to catch them
Mania, tries to escape
When spoken to often turns his head to wrong side.
Head
Vertigo on turning head suddenly
Feeling as if head were screwed up; walking caused the most severe sticking pains;
> towards 11 a.m., and disappeared by evening
Head very hot
Headaches of epileptics
Sticking pains in back of skull and over eyes, < every motion and stepping
Sticking l. temple on waking, extending into ear and eye;
> moving in open air
Headache, with flushed face, blindness, and delirium.
Eyes
Objects appear large, with red halo
Everything seems elongated, objects appear in a cloud
Clouds of flies; motes; bright spots; stars; flashes
Figures on carpet appear constantly and successively to rise in her face
Diplopia
Sharp neuralgic pains in and about eyes
At 9 p.m. eyelids heavy, difficult to keep open.
Face
Face hot and very red.—Deathly pallor.
Mouth
Mouth dry
Tongue thick; cannot articulate distinctly
Tongue semi-paralysed
Speech slow, embarrassed, stuttering, chattering.
Throat
Burning caused by coughing
Dryness
Dysphagia; swallowing causes paroxysms of suffocation
Throat dark red.
Stomach
Vomiting of food; after hot drinks; with severe sticking pains in umbilical region.—> After vomiting.—Region of stomach very sensitive; swelling in pyloric region.
Urinary Organs
Frequent micturition
Involuntary, but scanty; nocturnal enuresis
Cutting, drawing pains in l. ovary, extorting screams, > bending; ovary swollen and tender during menses
Epilepsy from ovarian irritation.
Heart
Failure of action from chloroform and other cardiac paralyzers.—Accelerated pulse.
Back
Burning in back under sternum and in region of stomach.—Spinal irritation, pressure causes pallor, nausea, belching, and retching.
Limbs
Numbness; heaviness; paralysis of limbs.
Generalities
Hyperaesthesia of some nerves: ophthalmic, auditory, olfactory, vaginal, spinal, solar-plexus, nerves of uterus and bladder.—Great desire for open air (faintness).—Very weak in the open air.—Giddiness and staggering.—> From motion.
Sleep
Disturbed by gastric pains
Restless through night
Waked by frightful dreams.