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Duboisinum

Clarke - Dictionary of Practical Materia Medica · John Henry Clarke · 6,797 chars · source ↗

All books on Duboisinum → Antidoted byCoffea Cruda
General

Duboisinum.

Duboisia myoporoides. Corkwood Tree. (Queensland.) N. O. Solanaceae. Tincture and solution of alkaloid prepared from extract of the leaves.

Clinical

Delirium. Drowsiness. Eyes: dilated pupils. Locomotor ataxy. Mouth, dryness of. Paralysis. Presbyopia. Throat, dryness of.

Vertigo

Vision, disorders of.

Characteristics

Duboisia belongs to the same order as Belladonna, and its alkaloid, Sulphate of duboisia, has been used as a substitute for Atropine. Its application to the eye has caused marked constitutional symptoms of fever, delirium, stupor, and dry mouth. A symptom which may prove a keynote is "a red spot floating in the field of vision." Guided by this, C. H.

Helfrich cured a case of hyperaemia of optic nerve with Duboisin 3 (N. A. J. H., xiii. 267).

Dryness of mucous membranes is very characteristic. Cool feeling in the eyes. Sensation as if stepping on empty space. Feeling of largeness in eyes, in tongue.

Inability to stand with the eyes shut gives it a place in locomotor ataxy. It has also been proved.

Relations

Antidoted by: Coffee; lemon-juice. Compare: Bell., Atrop., Dulc., Stram., &c. Anhalonium (coloured vision).

Mind

Excitable; tries to get off the sofa

Stupor; though if questioned replies, but with difficulty

Picks at surrounding objects; slight drawings up of arms; very rest less

Carphology; glances suspiciously under bed-clothes and behind back; left to himself upsets room in a few moments—towels, brushes, shoes placed on bed, and boots on dressing-table; throughout air of fun and humour; on recovery remembers nothing of what he had done

Busy delirium; plucks at collar of night-dress; gazes intently at foot of bedstead where no one is, reaches out toward imaginary person or object

Unable to concentrate thoughts on any subject; absent-minded thoughts wander from subject to subject; forgets what he started with thoughts silly, nonsensical

Unable to express herself.

Head

Dizziness; strange feeling in head, with nausea and darkly flushed face; the "strange" feeling lasted longer than the faintness and drowsiness ensued

Headache

Head feels light; vertigo on rising up or walking; great inclination to fall backward, esp. on going up stairs; almost impossible to stand with eyes shut

Head heavy, dizzy

Dull pain through upper part of eyeballs and forehead like sick-headache.

Eyes

Pupils widely dilated

Eyes feel cool

Sharp pain in upper eyeball

Eyes feel tired

Things seemed elevated; every time he looked up from his book a dull pain flies through upper part of eyeballs and forehead like sick-headache; eyes felt large and protruding

Faces repeated in all directions

Countenances of bystanders appear to have hollow cheeks; walls to have great hollows excavated in them

Hallucinations of vision: suddenly sits on ground imagining a chair ready for him; drops a glass in mid-air instead of placing it on the table; grasps in the air above his head for his watch which had been taken from him

Imagined it was quite dark when it was a bright summer afternoon

Cannot make out print within two feet, and it shows several colours-blue, orange, and reddish-brown, as does the ink when writing; pupils nearly normal; a + 20 glass makes reading at normal distance possible, but eyes feel strained in using it

Appearance of a red spot in field of vision moving with the eye

Hyperaemia of optic nerve; optic disc very red, small vessels visible, large vessels much enlarged and tortuous; accommodation paralysed; outline of disc indistinct; arteries diminished

Fluttering sensation in eyeball

Twitching of orbicularis palpebrarum

Eyes for the most part kept closed, but opened occasionally (in a prover).

Ears

Ringing in ears (esp. r.), comes on suddenly.

Nose

Nose very dry and stopped up.

Face

Face deep red.—Lips very dry.

Mouth

Tongue appears to swell; becomes too large for mouth, impeding speech

Tongue feels "flat"; cannot articulate distinctly

Excessive dryness in mouth and throat, can scarcely speak for it.

Throat

Throat dry; red; capillaries varicose; no secretion of any kind visible; in consequence of the dryness the follicles are very prominent, and the conformation of spinal column plainly visible; an almost perfect picture of "pharyngea sicca"; epiglottis hyperaemic; laryngeal cavity engorged, dry, with here and there patches of mucus, viscid, semi-transparent.

Next day larynx entirely dry, pharynx having isolated patches of adherent, yellowish-white mucus

Constant desire to clear throat

Great difficulty in swallowing, esp. empty swallowing.

Stomach

Loss of appetite, nausea.—Deadly "gone" feeling, as if at greater curvature, not > by eating or drinking; pulse feeble and intermittent.

Urinary Organs

Constant desire to pass water, with great difficulty in doing so

No urine passed; bowels inactive; bathed in sweat

Slight burning in urethra during micturition.

Respiratory Organs

Hoarseness

Hard, dry, hacking cough caused by tickling at about bifurcation of trachea; cough = feeling of soreness or rawness over whole of both lungs, esp. lower lobe l. and upper r.; cough not > or < by anything

Respiration puffy and noisy.

Heart

A rapid pulse

Faintness

Sense of oppression and longing to get rid of the medicine (immediately after the dose in a poisoning case); increased to agony

Agony of breathlessness and sense of impending death

Pulse rate falls on sitting up and increases on lying down

Pulse irregular and intermittent.

20, 21.

Back and Limbs

L. leg powerless, r. leg rigid

Arms frequently and involuntary jerked away from the sides

Dorsal and lumbar muscles thrown into violent rhythmic contractions

Loss of power in lower limbs; staggers as if drunk

Going down stairs or kerb-stones is difficult, every step jolting his back "as if he had stepped down from the top of a house."

Severe pressive pain in lumbar region in each side on waking, > on moving about

Peculiar sensation in legs, then in thighs, arms, and other parts of the body, as if they were asleep.

Generalities

Heaviness of limbs, esp. lower.—General weakness, disinclination to move.—Sense of lightness throughout body and head.—Unsteady gait, occasionally a feeling as if he had stepped on empty space, and would catch himself for fear of falling.—Staggered, had to concentrate his energy and look directly ahead, for on looking to one side there was disposition of falling to the other.—General trembling; unable to hold up head; hallucinations and nausea.

Sleep

Stupor which is not sleep, he replies if questioned

Sleepy

Drowsiness and rambling.

Fever

Complained of chilliness

Temperature 100.5°

Cold and chilly, wants to wear extra clothing, which makes him feel comfortable

Bathed in sweat.